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* In a Dragon deck, use multiple copies of this card. If you run out, use [[Monster Reincarnation]] to bring it back to your fusion deck and summon it again.
* If possible, set a [[De-Fusion]] or [[Compulsory Evacuation Device]]before or after summoning this card. It would could be deadly if your opponent takes control of this card, destroying you and your hard work.
* Use "cards such as [[Dark Hole]] or [[King DragunLightning Vortex]]" to give this card some protection against Spell and trap cardsclear the field, then use [[Dragon's Mirror]] to fuse a Five-Headed Dragon for a possible [[One Turn Kill]].
* Use "[[King Dragun]]" or "[[Lord of D.]] to give this card protection against Spell and Trap cards. * Use [[Future Fusion]] by sending 3 [[Blue-Eyes White Dragon]]s, [[Red-Eyes Darkness Metal Dragon]] and [[Red-Eyes Wyvern]] to summon [[Five-Headed_Dragon]]. Then use [[Dragon's Mirror]] to summon the [[Blue-Eyes Ultimate Dragon]]. During the End Phase, if you haven't normal summoned or set a monster, use [[Red-Eyes Wyvern]] to summon [[Red-Eyes Darkness Metal Dragon]]. It makes already 7300 total Atk, and in two turns, there will be 5000 more.
* You can [[Summon]] three copies of "[[Five-Headed Dragon]]" if you have "[[Future Fusion]]", two copies of "[[Dragon's Mirror]]", "[[Burial from a Different Dimension]]", and either "[[Miracle Dig]]" or a second copy of "Burial from a Different Dimension". First, use "Future Fusion" to send five [[Dragon]]-[[Type]] [[Monster Cards|monsters]] to your [[Graveyard]], then "Dragon's Mirror" to [[Removed from play|remove them from play]] and Summon the first "Five-Headed Dragon". Then use "Miracle Dig" and "Burial from a Different Dimension" (in that order) to return the monsters to your Graveyard so you can use another "Dragon's Mirror" to summon the second "Five-Headed Dragon". The third "Five-Headed Dragon" will be Summoned automatically in two [[turn]]s.
* You can tribute this monster for "[[Great Maju Garzett]]" to make "Great Maju Garzett" a 10,000 Attack monster. Use cards like "[[Raigeki]]" and , "[[Heavy Storm]]"/, "[[Giant Trunade]]" or any similar cards to clear the field, then "Great Maju Garzett" can attack directly, generally ending the duel.
* In a [[Cyberdark]] deck, discard this card with [[Fusion Guard]], then, when the moment comes, equip it to [[Cyberdark Dragon]], and use [[Limiter Removal]] for a 12000 ATK monster.
*Use the effect of [[Vanguard of the Dragon]] or [[Spirit Ryu]] to easily dump dragons into the graveyard for Dragon's mirror. *While facing off against a [[light]] orientated deck i.e. [[Lightsworn]]s and [[chaos]] you can side in a [[DNA Surgery]] and an [[honest]] or two to possibly game your opponent. *Use [[Monster Reincarnation]] to add this card back into the extra deck if it is destroyed.
* Also useful in a [[Dragunity]] deck for dumping Dragunity Dragons via [[Future Fusion]]. Use [[Future Fusion]] to dump at least [[Dragunity Phalanx]], [[Dragunity Brandistock]], [[Dragunity Corsesca]], [[Dragunity Pilum]], and 1 other Dragon-types of your choice (most notable [[Red-Eyes Darkness Metal Dragon]], [[Dragunity Arma Leyvaten]], or others like [[Dragunity Aklys]]). Try to Synchro Summon [[Dragunity Knight - Barcha]] and equip it with Dragunity Dragons that you just dumped earlier. Two turns after [[Future Fusion]]'s activation (assuming that this card survived), you'll get [[Five-Headed Dragon]] with 5000 ATK. With this, you'll have two monster with total (at least) 8000 ATK, enough for OTK.
* A good strategy to use if the time is availalbe is to use [[DNA Surgery]] to turn all monsters into dragon type, and use [[Blue Eyes Ultimate Dragon]] and [[Black Luster Soldier]] in the fusion process. Then use two cards such as [[Monster Reborn]] or [[Premature Burial]] to bring back both monsters, and fuse them into [[Dragon Master Knight]]. The second card gains attack from the first one, leaving you with 5,000 and 5,500 atk points respectively. Be aware however of cards such as [[Rainbow Neos]] which bypass your cards effects and can return your powerful monsters to your deck.
* a A near solid perfect way of bringing out three copies is to play [[Future Fusion]], dumping 5 Dragons into your graveyard. then activate [[Giant Trunade]] to bounce your Future fusion and activate it again, dumping a new dragon setof dragons. you You can then activate 2 [[Dragon's Mirror]] s and remove all 10 Dragons from play to summon 2 [[Five-Headed Dragon]]s. if the future fusion survives, in two turns you'll have 3 Dragon's ready to torment your opponentif you haven't won already.
*bringing Bringing out [[Stardust Dragon]] or [[King Dragun]] alongside [[Five-Headed Dragon]] can keep your f.h.d Five-Headed Dragon safe from deadly cards such as "[[Mirror Force]]" or "[[Dark Hole]]"