Card Trivia:Slifer the Sky Dragon
- This is the cover card of Quarter Century Anniversary Selection, and is also one of the cover cards of 2016 Mega-Tins, Battle Pack 2: War of the Giants, Millennium Box Gold Edition, Speed Duel: Battle City Box, Legendary Collection: 25th Anniversary Edition, and Speed Duel: Streets of Battle City.
- This monster appears in the artworks of "Quiz Panel - Slifer 10", "Quiz Panel - Slifer 20", "Quiz Panel - Slifer 30", "Thunderforce Attack", "The Revived Sky God", "Ultimate Divine-Beast", and the second artwork of "Raigeki".
- An engraving of this monster appears in the artworks of "Gravekeeper's Inscription" and "Gravekeeper's Oracle".
- This card's Japanese name, "The Sky Dragon of Osiris" (オシリスの
天 空 竜 Oshirisu no Tenkūryū), is based on Osiris, the god of life, death, and fertility in ancient Egyptian religion.- This card's English name, "Slifer the Sky Dragon", is based on Roger Slifer, an employee of 4Kids Entertainment.
- This card is the only Egyptian God to have its name changed in the TCG.
- This card has a Wicked God counterpart: "The Wicked Eraser".
- This card has a Sacred Beast counterpart: "Uria, Lord of Searing Flames".
- The name, appearance and ATK-gaining effect of "Ascension Sky Dragon" are based on this card.
- The Illegal version of this card is the only card to have a red frame.
- In the Japanese version of the Yu-Gi-Oh! anime, the original version of this card and the other Egyptian Gods were in English, while still having their Japanese names.
- "Defense" was also misspelled as "Difence" on this card and the other Egyptian Gods' card text.
- This monster and Yami Yugi appear in page 12 of chapter 104 of the Bobobo-bo Bo-bobo manga, by Yoshio Sawai.
- The corresponding episode of the anime used a different gag instead, as Toei Animation, who produced the anime of Bobobo-bo Bo-bobo, no longer had the rights to Yu-Gi-Oh!.
- In the Yu-Gi-Oh! Millennium World manga, this card was also known as "The Dragon King of the Sky" (
天 空 の竜 王 Tenkū no Ryūō).
- The background of this card's artwork was used in the Yu-Gi-Oh! Forbidden Memories video game as one of the Forbidden Ruins wall designs.
- The international version of Forbidden Memories replaces the hexagrams in the background with hexagons; the TCG release does not alter this detail.
- The card artwork for this card's Illegal version is taken from Yu-Gi-Oh! Duel 172 (Duelist Duel 113): "Summon the Nightmare", specifically from the panel showing this monster being Summoned.
- This card's second alternative artwork is based on this monster's pose in a flashback in the Yu-Gi-Oh! The Dark Side of Dimensions movie.
- This monster shares similarities with "Arcana Triumph Joker".