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The Deck focuses on lowering the opponent's monsters' ATK with "Venom Swamp" and Summoning "Vennominon the King of Poisonous Snakes" or "Vennominaga". Since the ATK of both cards are dependent on the number of Reptiles in your Graveyard, cards like "Foolish Burial" and "Snake Rain" are important in this Deck. Also, there are not many "Venom" monsters, so a hybrid with other Decks is inevitable.
"Venom Swamp" is able to quickly weaken and eventually destroy any non-"Venom" monster. Also, even if "Venom Swamp" is not on the field, "Venom Burn" can inflict serious damage to a player's Life Points"
The Deck relies on "Venom Swamp" for Venom Counters to have any effect on monsters, so if "Venom Swamp" is destroyed, Venom Counters are almost useless. This bad situation can be avoided by "Spell Reclamation".
The main weakness of the "Venom" Deck is the low ATK points of most "Venom" monsters. This means that your opponent can easily just Summon a monster to destroy your "Venom" monster.
Another weakness of this Deck is "Zombie World". This card makes the ATK of "Vennominaga" become 0, and when it is destroyed by battle there are no Reptile monsters in the Graveyard to banish in order to Special Summon it again.
Since the Deck relies on Reptile monsters being sent to the Graveyard, it is at its most vulnerable when banish strategies are used, like "Dimensional Fissure".
"Venom" Decks are at risk of losing LP early, since the only reliable methods for quickly Summoning "Vennominon" from the Deck involve taking damage (either via "Damage = Reptile" or "Damage Condenser").