Card Trivia:Giant Germ
- This monster's appearance is based on the largest-known germ, Balantidium coli, the only ciliate phylum infectious to humans.
- This monster's effects may be elucidated based on the following:
- This monster's effect activating upon being destroyed and inflicting effect damage reflects how a host's immune system fights off "germs", which in-part often raises the entire body's temperature to do so, in addition to the germ releasing its payload of symptoms to make the host feel ill.
- This monster's Special Summoning effect reflects how most, if not all germs (especially this one as it is based on a bacterium) undergo mitosis, an asexual reproductive process by which a cell creates an identical copy of its own chromosomes and bisects itself into two cells each with the same chromosome information.
- This monster appears to be the opposing counterpart to "Nimble Momonga", who debuted in the same set as it, Pharaoh's Servant:
- Both monsters share the same original ATK and DEF (1000/100).
- Both monsters feature an effect that manipulates Life Points upon being destroyed. This monster decreases the opponent's Life Points, while "Nimble Momonga" increases the player's Life Points.
- Both monsters feature effects that Special Summons multiple copies of itself from the Deck. This monster Special Summons multiple copies of itself in face-up Attack Position, while "Nimble Momonga" Special Summons multiple copies of itself in face-down Defense Position.
- In the Yu-Gi-Oh! World Championship games, when this monster is in Defense Position, it becomes green and shrinks a bit.