Card Trivia:Red Medicine
- A diagram of the bottle in this card's artwork appears in the artwork of "Chemical Cure Red".
- This card is tied with other cards as the first Spell Card and the first card with a Life Point-gaining effect in the OCG/TCG.
- This card has a counterpart: "Blue Medicine".
- Both cards are references to items of the same names in The Legend of Zelda series.
- This card has a polar opposite damage counterpart: "Hinotama".
- This is one of the first Spell Cards seen on-screen in the Yu-Gi-Oh! anime, along with "Block Attack", "Mooyan Curry", "Polymerization", and "Remove Trap".
