- This card can be searched via "Sangan", "Last Will", "Witch of the Black Forest", "Giant Rat" and "Gokipon".
- Avoid flipping "Man-Eater Bug" while your opponent has no monsters or you'll have to destroy one of your own.
- It is generally considered better to play "Old Vindictive Magician" than "Man-Eater Bug" because Spellcasters have arguably more support, and "Apprentice Magician" is insanely easy to play. After having any number of "Apprentice Magician" destroyed by battle, simply summon a "Old Vindictive Magician" to destroy the monster giving you trouble.
- A small advantage that this card has over "Old Vindictive Magician" is that if you are being effected by a card such as "Ground Collapse" and need to clear a space in order to summon something such as "Breaker the Magical Warrior" to destroy "Ground Collapse" you can have Man-Eater Bug choose to destroy itself or any other monster you control.
- Using"Verdant Sanctuary", you can add another copy of this card to your hand from your deck as soon as the first one is destroyed,provided it wasn't destroyed while face-down.
- Use this card to destroy Yubel, so you can Special Summon its advanced forms.