In a "Fluffal" Deck, this card can be used to Fusion Summon "Frightfur Sabre-Tooth" using 3 or more Fusion Materials, so that it will not be destroyed during the End Phase.
It is more useful to perform this Fusion Summon during the Battle Phase, after attacking, in order to attack with the newly Fusion Summoned "Sabre-Tooth" and with the "Frightfur" Fusion Monster Special Summoned by its effect.
This card is more useful on Fusion Summoning monsters that can't be destroyed by card effects, such as "Ultimate Axon Kicker", to avoid this card's End Phase drawback.
In a "Melodious" Deck, this card can be used to Fusion Summon "Bloom Diva the Melodious Choir", whose effect will protect itself from this card's effect that would destroy it.
With "Mound of the Bound Creator" active, this card can be used to Fusion Summon a Level 10 or higher monster, so that it won't be destroyed during the End Phase.
After equipping at least one of two Gemini monsters on your field with "Supervise" and attacking with both, Fusion Summon "Superalloy Beast - Raptinus" using the equipped monster as material. "Supervise" will then revive a Normal Monster or Gemini monster from your Graveyard to bring even more damage potential.
Since the Summoned Gemini will have its effect thanks to "Raptinus", "Chthonian Emperor Dragon" is a good option, bringing two attacks for a combined 4800 extra damage on top of 2200 from "Raptinus". If the material of "Supervise" was "Chthonian Emperor Dragon", the damage potential for the combo exceeds 11,800.
Another good option if the above is lacked, "Gigaplant", for post-battle effect use.
Also, "Gemini Soldier" can Summon lower Level Gemini monster from the Deck for more varied utility purposes.