"Miniaturize" can be used on a Level 5 monster to make it vulnerable to this card's effect, "Demotion" can be used on a Level 6 monster, and "Level Retuner" can be used on both Level 5 and 6 monsters. "Synchro Boost" can be used on Level 3 monsters.
A well timed use of this card's effect could possibly devastate an opponent using an Anti-Meta deck, as most cards used are Level 4 (just be wary of "Doomcaliber Knight" and "Skill Drain".)
It can also be efficient against "A-to-Z" and "Heraldic Beast" Decks as all their base monsters are Level 4.